Formulated to target the root cause of aging
Better Cells
Anti-inflammatory
Better Heart
Better Brain
What's inside?
🌾Spermidine – reduces inflammation, improves cognition, and has shown to have protective effects from neurodegeneration. Studies show it boosts immunity and helps prevent age-associated cardiovascular disease. Humans with higher levels of spermidine have a 5 year increase in life expectancy, as reflected in a 20-year epidemiological study. However, spermidine levels decrease with age, but can be increased by supplementation.
🥦Dihydroquercetin, – A more potent form of quercetin. It plays a vital role in supporting the health and functionality of cells, while also assisting the body in maintaining proper protein function and stability.
🥬Luteolin – is believed to confer longevity benefits, as it has multiple biological effects such as anti-inflammation, anti-allergy and anti-cancer, luteolin functions as either an antioxidant or a pro-oxidant biochemically.
Not all supplements are the same
We were dissapointed with our options on the market, so we set out to do it the right way, transparently delivering powerful ingredients that hold potential to impact human health and longevity.
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| Third party lab tests for every batch |
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| Science backed ingredients |
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| Target root causes of aging |
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| Cold storage in warehouse |
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| Made in America |
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The Breakdown
WTF is Autophagy?
As we age we accumulate zombie cells – old damaged cells that linger beyond their useful life. These zombie cells infect other healthy cells, speeding up the aging process. Everything from hair loss, wrinkles, arthritis, cancer, dementia and so on (aging) occurs.
What scientists have realized is that when we induce autophagy, these zombie cells are starved of energy and die, so your future looks healthier and longer.
Oxidative Stress
As we age, it becomes increasingly important to maximize our cellular health, and ensure our cells are functioning optimally – after all, our body is made up of trillions of cells that form our tissues, which form our organs, and which dictate many facets of our overall health. Unfortunately, cells often go awry due to disease, the aging processes, oxidative stress and environmental exposures: our diet, lack of nutrients, lack of oxygen, any exposure to toxins, and much more. Cellular damage can lead to chronic inflammation and accelerated aging.
Promoting Autophagy
The promotion of cellular health and clean-up is necessary to slow the processes of aging, as well as to prevent chronic inflammation and the development of disease. In promoting optimal cellular health it is important to promote proper regulation of autophagy, apoptosis, mitophagy, and mitochondrial biogenesis as well as to prevent long-term oxidative stress which causes cellular damage, dysfunction and inflammation.
Deep dive on spermidine
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FAQ
When and how should I take Clean Being?
Take two capsules per day, with or without food.
How many capsules are in a pack?
Each pack of Clean Being contains a 30 day supply – each daily dose contains:
– 250 mg of Luteolin, a naturally occurring polyphenol.
– 50 mg of Dihydroquercetin, the most potent form of quercetin.
– 6mg of Spermidine, a potent autophagy inducer.
Is Clean Being vegan, gluten free, and keto-friendly?
Yes, Clean Being is vegan, gluten free, and keto-friendly 🌱.
What is autophagy?
Autophagy is a cellular clean-up, salvage and recycling mechanism which removes damaged cells (including diseased cells) and cellular parts, in order to promote the proper functioning of cells.
What is apoptosis?
Apoptosis is a necessary cellular process to end a cell’s life; it is known as ‘programmed cell death’.
This built-in cellular process is necessary to eliminate dysfunctional cells and make way for new healthy cells.
Certain pro-aging cells can develop resistance to apoptosis, such as senescent cells (contribute to disease) and cancer cells. Thus, when apoptosis is not effective, dysfunctional cells can replicate and cancer may develop.
The dysregulation of cellular death likely accelerates the aging processes. To support healthy apoptosis, look into fasting, and phytochemicals like: luteolin, resveratrol, spermidine and sulforaphane.
Benefits beyond the cell
Autophagy
Spermidine has been shown to induce autophagy, suggesting that this cytoprotective process may be responsible for the beneficial effects of spermidine administration. [1]
Evidence suggests that in animal models of Alzheimer’s disease(AD) and cancer, quercetin is able to induce cellular autophagy, the body’s process of clearing out damaged cells. [2]
Inflammation
In animal studies, luteolin has been shown to prevent inflammation of the lungs, nose and brain via the inhibition of pro-inflammatory cytokines. [1] [2]
In mice, luteolin also prevents viral-induced inflammation in the breast and lung. [3] [4]
Quercetin and its derivatives fight inflammation, as well as to activate NrF2, increase glutathione levels, and scavenge free radicals. [5]
Heart
Individuals who supplemented with spermidine had lower blood pressure. [1]
Lower spermidine and spermine levels were associated with higher cardiovascular disease-related mortality rate. [2]
Luteolin supports heart health and studies have shown that luteolin strengthens heart cells and heart contractions. [3]
Dihydroquercetin has been shown to promote heart health in healthy human volunteers via lowering LDL cholesterol. [4]
Brain
Supplementation with spermidine has been shown to protect against neurodegeneration. [1]
In mice, spermidine was also shown to reduce dementia (in a mouse model of frontotemporal lobar dementia). [2]
Luteolin has been shown to have neuroprotective effects and to support nerve development. This effect is likely due to luteolin’s ability to suppress brain inflammation and deter oxidative stress.
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